I cannot locate any definitive studies clearly demonstrating fluoxitine (Prozac) ototoxicity in humans or animals. I have reviewed only one report with some ''subjective information'' along those lines. As widely used as Prozac is, it would be surprising if there was a significant incidence of ototoxicity that would not be clearly apparent by now. However some medications have been found to have an extremely low incidence of a given side effect that delays identification of it and its relationship to the drug. Also a particular side effect may only occur in a certain subset of individuals or only in combination with other factors. Therefore, I cannot offer a ''yes'' or ''no'' response. I recommend that the best source of information for you is your physician, and I urge you to review this with him/her.